The Charmed actress voiced her disappointment in the famed talk show host in a tweet including a photo of Winfrey posing with disgraced Hollywood producer Harvey Weinstein.
“I am glad more are seeing the ugly truth of @Oprah,” McGowan, 47, tweeted along with an old picture of the pair at the 2014 Critics Choice Movie Awards. “I wish she were real, but she isn’t.
“From being pals with Weinstein to abandoning & destroying Russell Simmon’s [sic] victims, she is about supporting a sick power structure for personal gain, she is as fake as they come. #lizard.”
McGowan was one of the first women to accuse Weinstein of rape.
It’s believed her remarks refer to Winfrey’s near-involvement in a documentary on the life of Russell Simmons. The music executive has been accused of rape and sexual misconduct by at least 20 women.
“I have decided that I will no longer be an executive producer on the untitled Kirby Dick and Amy Ziering documentary, and it will not air on Apple TV+,” Winfrey said in a statement to the Hollywood Reporter in January last year.
“I want it to be known that I unequivocally believe and support the women. Their stories deserve to be told and heard. In my opinion, there is more work to be done on the film to illuminate the full scope of what the victims endured, and it has become clear that the filmmakers and I are not aligned in that creative vision.”
As for Weinstein, Winfrey has revealed on several occasions she had no prior knowledge of his history of sexual abuse. She is yet to respond to McGowan’s Twitter comments.
In March, Weinstein was convicted of rape and a criminal sexual act. He was sentenced to 23 years in jail.