“Despite a deep love and respect for one another, we have realised that our current paths have taken us in opposite directions,” they said.
The pair added they hoped to keep their separation “private” and be “forthcoming in our truth together.”
They clarified “there is no anger or animosity, quite the contrary.”
The statement said the pair’s split was a mutual decision made through an “immense amount” of “respect and consideration.”
The couple stated they will not be sharing additional information on the matter.
Cuoco began dating Cook, an equestrian, in 2016. The pair got engaged on her birthday in November the following year.
After marrying in a horse stable in California on June 30, 2018, the couple were often public about their relationship on social media.
Just in June, they shared three-year wedding anniversary celebrations on their respective Instagram pages.
“NY, June 30th, 2016 is the year we met,” the Flight Attendant star wrote in a throwback photo of the two.
“2 years to the day before we got married and now 3 years married! Why have you stayed married to me for so long?! I’m sincerely impressed @mrtankcook lol I love you oh so much you have no idea…happy anniversary!!!”
Cook wrote in his own post, “I agree @kaleycuoco I am just as amazed it’s been been three years, feel like just a flash.”
“I love you so much and I can’t wait for a million more years!!”
Cuoco was previously married to Ryan Sweeting for just 21 months.
“I honestly thought I wouldn’t get married again,” she told Cosmopolitan at the time. “My ex ruined that word for me. I married someone the first time who completely changed. The person I ended up with was not the person I originally met. And that wasn’t my fault — that was his.
“I knew how much I had to give and how much I wanted to receive.I knew I just had to be patient … I had to go through a lot of things, but it brought me to Karl.”
For a daily dose of 9Honey, sign up here to receive our top stories str ht to your inbox